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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK14
All Species:
38.48
Human Site:
T241
Identified Species:
70.56
UniProt:
Q16539
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16539
NP_001306.1
360
41293
T241
L
I
L
R
L
V
G
T
P
G
A
E
L
L
K
Chimpanzee
Pan troglodytes
Q95NE7
360
41475
T241
Q
I
M
R
L
T
G
T
P
P
A
Y
L
I
N
Rhesus Macaque
Macaca mulatta
XP_001112423
329
37756
N226
I
S
S
E
S
A
R
N
Y
I
Q
S
L
T
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P47811
360
41269
T241
L
I
L
R
L
V
G
T
P
G
A
E
L
L
K
Rat
Rattus norvegicus
P70618
360
41303
T241
L
I
L
R
L
V
G
T
P
G
A
E
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232616
360
41440
T241
L
I
L
R
L
V
G
T
P
G
P
E
L
L
K
Frog
Xenopus laevis
P47812
361
41700
T242
L
I
L
R
L
V
G
T
P
E
P
E
L
L
Q
Zebra Danio
Brachydanio rerio
Q9DGE2
361
41614
T242
Q
I
M
R
L
T
G
T
P
P
S
S
L
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61443
365
42080
T244
L
I
M
E
V
L
G
T
P
A
D
E
F
M
S
Honey Bee
Apis mellifera
XP_395384
360
41360
T237
L
I
M
E
I
L
G
T
P
R
D
E
F
M
Q
Nematode Worm
Caenorhab. elegans
Q17446
377
43900
T252
R
I
M
S
V
T
G
T
P
D
E
E
F
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
S235
I
I
T
D
L
L
G
S
P
P
K
D
V
I
N
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
T232
I
I
T
E
L
L
G
T
P
P
D
D
V
I
N
Conservation
Percent
Protein Identity:
100
96.1
89.4
N.A.
N.A.
99.4
98.6
N.A.
N.A.
96.3
88.3
85.8
N.A.
68.4
75
62.8
N.A.
Protein Similarity:
100
97.7
90.8
N.A.
N.A.
99.4
99.1
N.A.
N.A.
98.6
94.7
92.2
N.A.
80.2
85
76.6
N.A.
P-Site Identity:
100
53.3
6.6
N.A.
N.A.
100
100
N.A.
N.A.
93.3
80
46.6
N.A.
40
40
46.6
N.A.
P-Site Similarity:
100
66.6
20
N.A.
N.A.
100
100
N.A.
N.A.
93.3
86.6
66.6
N.A.
66.6
73.3
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.9
50.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.9
69.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
31
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
24
16
0
0
0
% D
% Glu:
0
0
0
31
0
0
0
0
0
8
8
62
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% F
% Gly:
0
0
0
0
0
0
93
0
0
31
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
24
93
0
0
8
0
0
0
0
8
0
0
0
31
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
39
% K
% Leu:
54
0
39
0
70
31
0
0
0
0
0
0
62
47
0
% L
% Met:
0
0
39
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% N
% Pro:
0
0
0
0
0
0
0
0
93
31
16
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
24
% Q
% Arg:
8
0
0
54
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
8
8
8
0
0
8
0
0
8
16
0
0
16
% S
% Thr:
0
0
16
0
0
24
0
85
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
16
39
0
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _